Membrane Filter

PVDF Membrane Filter

PVDF membrane filters are designed for high-performance liquid and gas filtration in analytical and biotech applications. Available in hydrophobic and hydrophilic variants, with or without a PET support layer, they offer high chemical resistance, thermal stability, and low protein binding. The hydrophobic version enables fast air flow for venting and gas purification, while the hydrophilic version ensures high recovery of proteins and sensitive biomolecules in aqueous and mixed-phase samples. The filters are suitable for sterilization by autoclave, ethylene oxide, E-beam, and gamma irradiation.

Hydrophobic PVDF provides fast air flow and excellent performance in gas venting and air filtration
Hydrophilic PVDF minimizes protein binding and maximizes recovery in cell culture, serum, and diagnostic reagent applications
PET-supported membranes offer enhanced mechanical strength for high-pressure or abrasive filtration tasks
Un-supported membranes provide high porosity and permeability for low-resistance liquid and gas flow

Key Benefits

What This Product Gives You

Hydrophobic PVDF provides fast air flow and excellent performance in gas venting and air filtration
Hydrophilic PVDF minimizes protein binding and maximizes recovery in cell culture, serum, and diagnostic reagent applications
PET-supported membranes offer enhanced mechanical strength for high-pressure or abrasive filtration tasks
Un-supported membranes provide high porosity and permeability for low-resistance liquid and gas flow
Compatible with pH 2-10 and a wide range of organic solvents, acids, and bases due to high chemical resistance

Available in hydrophobic and hydrophilic variants with or without PET support
Supports pore sizes from 0.1 to 5.0 micron across disc, roll, sheet, strip, and customizable formats
Maximum operating temperature of 90°C for both supported and unsupported membranes
Operates effectively across pH 1-13, including aggressive acids and bases
High porosity and permeability reduce filtration time and pressure drop
Compatible with autoclave, ethylene oxide, E-beam, and gamma irradiation sterilization
No need to distinguish front and back side during assembly for disc formats

Where It Is Used

Applications And Buyers

Application Scenarios

Sterilizing air or gas in medical device venting systems using hydrophobic PVDF
Clarifying cell culture media and buffer solutions with hydrophilic PVDF to maintain protein integrity
Filtering acidic or basic solvents in HPLC and GC sample preparation without membrane degradation
Pre-filtration of diagnostic reagents and ophthalmic solutions where low protein binding is critical
Handling high-viscosity or particulate-laden samples with supported PVDF membranes for improved durability

Who It Is For

Pharmaceutical and biotech labs requiring low protein binding for assay accuracy
Medical device manufacturers needing reliable venting filters for sterile packaging
Environmental and food testing labs processing aggressive solvents and mixed-phase samples
Contract labs running high-throughput assays where membrane consistency and sterility are essential
OEMs developing filtration systems for diagnostic instruments or lab-on-a-chip devices

Problems It Solves

Protein loss during filtration due to high binding on non-specific membranes
Slow air flow or clogging in venting filters caused by low permeability or hydrophobicity
Membrane failure under high pressure or chemical exposure due to poor mechanical or chemical resistance
Inconsistent lot-to-lot performance affecting method reproducibility
Difficulty in handling mixed aqueous and organic samples without switching membrane types

Data

Specifications

Membrane Material	Polyvinylidene Fluoride (PVDF)
Wettability	Hydrophobic, Hydrophilic
Support Layer	PET supported, Unsupported
Pore Size	0.1, 0.22, 0.45, 0.65, 0.8, 1.0, 2.0, 3.0, 5.0 micron
Max Operating Temperature	90°C
pH Range	1-13
Membrane Format	Disc, Roll, Sheet, Strip, Customizable
Thickness	100±10 μm (Unsupported), 120±10 μm (Supported)
Sterilization Compatibility	Autoclave, Ethylene Oxide, E-beam, Gamma irradiation
Bubble Point (Hydrophobic)	0.55-0.6 bar (0.1 μm), 0.4-0.45 bar (0.22 μm), 0.25-0.3 bar (0.45 μm), 0.2-0.23 bar (0.65 μm), 0.13-0.16 bar (0.8 μm), 0.1-0.13 bar (1.0 μm)
Water Flow Rate (Hydrophilic)	≥6 ml/min/cm² (0.1 μm), ≥11 ml/min/cm² (0.22 μm), ≥30 ml/min/cm² (0.45 μm), ≥60 ml/min/cm² (0.65 μm), ≥100 ml/min/cm² (0.8 μm), ≥150 ml/min/cm² (1.0 μm)
Alcohol Flow Rate (Hydrophobic)	≥3.5 ml/min/cm² (0.1 μm), ≥7.5 ml/min/cm² (0.22 μm), ≥14 ml/min/cm² (0.45 μm), ≥36 ml/min/cm² (0.65 μm), ≥49 ml/min/cm² (0.8 μm), ≥61 ml/min/cm² (1.0 μm)

Materials

Polyvinylidene Fluoride (PVDF) membrane
PET support layer (for supported variants)
No specific resin or polymer grade named beyond PVDF and PET

Customization Options

Custom membrane formats including disc, roll, sheet, strip, and bespoke sizes
Custom pore sizes and thicknesses available upon request
Private-label packaging and part numbering through the OEM division
OEM contract manufacturing and membrane die-cutting services available

How It Is Made

Manufacturing And Quality Control

Manufacturing Process

Membrane die-cutting from roll stock to disc, sheet, or strip formats
Precision alignment and assembly of supported membranes with PET backing
Quality inspection of pore size and surface integrity
Sterilization compatibility testing for autoclave, E-beam, and gamma irradiation
Packing in specified quantities per product code

Quality Control

Pore size verified against specification using bubble point and flow rate tests
Membrane integrity checked for defects and uniformity before packing
Lot-to-lot consistency confirmed through batch testing
Sterilization compatibility validated for all listed methods
Packaging verified per order information and part number

Comparison

Compared With The Alternatives

Versus PTFE membranes

PVDF offers better mechanical strength and easier handling than PTFE, especially in unsupported forms, while maintaining high chemical resistance

Versus Nylon membranes

PVDF has superior chemical resistance to strong acids, bases, and organic solvents compared to nylon

Versus CA and RC membranes

PVDF withstands a wider pH range and higher temperatures than cellulose acetate and regenerated cellulose

Versus Unsupported membranes

PET-supported PVDF provides greater mechanical strength for high-pressure or abrasive applications, though at slightly reduced flow rate

Use Guide

How To Use It

Select hydrophobic PVDF for air, gas, and solvent venting where fast flow and low resistance are needed
Choose hydrophilic PVDF for aqueous solutions, cell culture media, and protein-containing samples to minimize binding
Use supported PVDF for high-pressure or abrasive filtrations where mechanical strength is critical
Verify pore size based on particle size: 0.22 micron for sterile filtration, 0.45 micron for general clarification
Ensure the filtration system is compatible with the maximum operating temperature of 90°C
Do not exceed the specified pressure limits; monitor flow rate for signs of blockage
Sterilize using autoclave, ethylene oxide, E-beam, or gamma irradiation as required

Photos

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FAQ

Questions Buyers Ask

What is the difference between supported and unsupported PVDF membranes?

Supported PVDF has a PET backing layer that increases mechanical strength for high-pressure or abrasive applications. Unsupported PVDF has higher porosity and flow rate but less structural integrity.

Which PVDF membrane should I use for protein samples?

Use hydrophilic PVDF for protein samples, as it has low protein binding and high recovery, especially in buffers, cell culture media, and serum.

What pore sizes are available?

Available pore sizes are 0.1, 0.22, 0.45, 0.65, 0.8, 1.0, 2.0, 3.0, and 5.0 micron across all formats.

How are the filters packed?

Discs are packed in 200, 100, or 50 pieces per pack depending on diameter. Rolls are packed as one roll per pack. Custom packing is available via OEM services.

Can I get custom sizes or formats?

Yes, custom disc diameters, roll sizes, and formats such as sheets and strips are available upon request through the OEM division.