Membrane Filter Material Selection Guide

Choose RC Membrane For Low Binding And High Purity

Regenerated cellulose (RC) membrane offers ultra-low non-specific binding and minimal extractables, making it ideal for trace-level analysis and biological sample preparation. Its natural hydrophilicity eliminates the need for wetting agents, reducing contamination risk in HPLC and GC sample clean-up.

RC Handles Both Aqueous And Organic Solvents

RC membrane maintains integrity across aqueous solutions and a broad range of organic solvents, including methanol, acetonitrile, and acetone. This compatibility supports solvent preparation and mixed-phase filtration without membrane degradation or extractable release.

Low Protein Binding Improves Recovery

RC's very low protein binding capability ensures high recovery of proteins, peptides, and low-concentration biomolecules. This makes it suitable for tissue culture filtration, diagnostic reagent processing, and biological sample analysis where analyte loss must be avoided.

RC Pore Sizes Match Your Filtration Need

Available in 0.1, 0.22, 0.45, 0.8, and 1.0 micron pore sizes, RC filters support particle removal from solvents, routine microbiological quality control, and fine precipitate retention. Use 0.22 micron for sterile-grade filtration and 0.45 micron for standard HPLC column protection.

RC Flow Rates Reflect Microporous Structure

At 25°C and 0.07 MPa pressure, RC membranes deliver water flow rates from 3.5 ml/min/cm² (0.1 μm) to 61 ml/min/cm² (1.0 μm). Higher flow rates at larger pores reduce filtration time without compromising retention for typical analytical applications.

PVDF Offers Hydrophobic And Hydrophilic Options

PVDF membrane is available in hydrophobic and hydrophilic grades. Hydrophobic PVDF enables fast air flow and is ideal for venting, gas purification, and sterile filtration of medical devices. Hydrophilic PVDF supports aqueous and mixed-phase fluid clarification with low protein binding.

PVDF Withstands Harsh Chemicals And High Temperatures

PVDF membrane resists organic solvents, acids, bases, and oxidation. It operates up to 90°C and maintains stability across pH 1-13. This makes it suitable for cleaning-in-place (CIP) processes, solvent recovery, and high-temperature filtration.

Supported PVDF Has Better Mechanical Strength

PVDF with a PET support layer offers enhanced mechanical strength compared to unsupported versions. This improves durability during high-pressure filtration and handling, especially for large-diameter discs used in industrial or high-volume lab workflows.

PVDF Flow Rates Exceed RC In Key Applications

Hydrophilic PVDF delivers water flow rates from 6 ml/min/cm² (0.1 μm) to 150 ml/min/cm² (1.0 μm) at 25°C and 0.07 MPa. This exceeds RC performance in high-throughput applications such as buffer and cell culture medium clarification.

Sterilization Compatibility Ensures Process Safety

This allows integration into validated sterilization processes for pharmaceutical, diagnostic, and biotech workflows without compromising membrane integrity.