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SPE Column

SPE Column

Single-use SPE columns for sample preparation in HPLC, GC, and environmental analysis, available in 3 mL and 6 mL formats with six sorbent types.

Full Range

All 7 SPE Column Products

Application

Where This Category Fits

Who It Is For

  • Pharmaceutical QC laboratories preparing drug metabolite samples for bioanalytical testing
  • Environmental laboratories extracting pesticides and organic contaminants from water and soil
  • Food and beverage testing labs isolating residues from complex matrices like milk and juice
  • Life-science laboratories purifying proteins and nucleic acids from cell lysates
  • Lab distributors and OEM brands needing a consistent, reproducible SPE column range

Problems It Solves

  • Sample matrix interferences cause baseline noise and false positives in chromatographic analysis
  • Inconsistent recovery rates across batches due to variable sorbent packing density
  • SPE columns from multiple suppliers require different elution protocols and hardware
  • Column breakthrough occurs when sample volume exceeds capacity, leading to analyte loss
  • Poorly sealed columns allow solvent leakage during vacuum or pressure application
Advantages

Why Buy This Range From Microlab

  • Six sorbent types in 3 mL and 6 mL formats allow method flexibility without changing column geometry
  • Injection-moulded housing with consistent packing across the range, reducing batch-to-batch variation
  • Pre-packed, sealed columns eliminate the need for on-site packing and reduce user error
  • Vacuum-compatible design with consistent flow rate across the range, suitable for automated systems
  • OEM printing and private-label packing available through the in-house OEM division
  • Solid-phase extraction of trace pharmaceuticals from wastewater samples
  • Clean-up of plasma and serum samples before LC-MS/MS bioanalysis
  • Isolation of pesticide residues from fruit and vegetable extracts
  • Pre-concentration of environmental contaminants in groundwater samples
  • Sample preparation for GC-MS analysis of volatile organic compounds
Knowledge

Related Guides

FAQ

Frequently Asked Questions

Which SPE column sorbent should I use for polar compounds?

Use reversed-phase C18 for non-polar to moderately polar compounds. For polar analytes, consider ion-exchange or mixed-mode sorbents depending on the charge and functional groups.

What is the maximum sample volume for a 3 mL SPE column?

The maximum recommended sample volume is 10 mL for most applications, but this depends on the matrix and analyte concentration. For high-load samples, use the 6 mL column.

Can I reuse an SPE column?

No. SPE columns are single-use and pre-packed. Reuse risks carry-over, breakthrough, and inconsistent recovery.

Do you offer SPE columns under our own brand?

Yes. The OEM division supports OEM plastic devices, contract manufacturing, and private-label packing for SPE columns.

How are SPE columns packed?

Each column is pre-packed, sealed, and packed in 100 units per box. The sorbent type and format are printed on the housing for bench-level identification.

Specify The Right SPE Column Part

Send the application and the volume and we will confirm the part number before you order.