Membrane Filter

PES Membrane Filter

PES Membrane Filters are designed for high-flow, low-adsorption filtration in life science and analytical applications. Made from polyethersulfone with an inherently hydrophilic surface, they deliver consistent performance across a wide range of pore sizes and operating conditions. The asymmetric structure provides high porosity and mechanical strength, enabling fast flow rates and long service life. These filters are suitable for sterile filtration of protein solutions, tissue culture media, and high-temperature liquids, with low extractables and minimal protein binding.

Inherently hydrophilic surface enables rapid wetting without surfactants
Low protein and drug adsorption preserves sample integrity in biological assays
High flow rates at low pressure reduce filtration time and improve throughput
Wide pore size range from 0.1 to 5.0 micron supports diverse particle retention needs

Key Benefits

What This Product Gives You

Inherently hydrophilic surface enables rapid wetting without surfactants
Low protein and drug adsorption preserves sample integrity in biological assays
High flow rates at low pressure reduce filtration time and improve throughput
Wide pore size range from 0.1 to 5.0 micron supports diverse particle retention needs
Consistent performance across lots ensures method reproducibility
High mechanical strength allows compatibility with various filter housings and assembly methods

Material: Polyethersulfone (PES), modified polymer with asymmetric structure
Wettability: Inherently hydrophilic, no surfactants required for wetting
Color: White, plain surface
Membrane formats: Disc, Roll, Sheet, Strip, Customizable
Thickness: 100±15 μm
Maximum operating pressure: 4.2 bar at 23°C
pH range: 6-13
Sterilization compatibility: Autoclave, Ethylene Oxide, E-Beam, Gamma irradiation
Endotoxin levels: <0.25 Eu/ml (tested using 400 cm²/400 ml S.W.F.I. per LAL)
Extractables: <1% (<0.015 mg/cm²)
BSA protein binding: <20 μg/cm²
Water flow rate at 25°C and ΔP = 0.07 MPa: >5 ml/min/cm² (0.1 μm), >8 (0.22 μm), >18 (0.45 μm)
Bubble point: ≥3.4 bar (0.1 μm), ≥2.7 (0.22 μm), ≥1.9 (0.45 μm), ≥1.1 (0.65 μm), ≥0.8 (0.8 μm), ≥0.6 (1.0 μm), ≥0.4 (1.2 μm), ≥0.4 (5.0 μm)

Where It Is Used

Applications And Buyers

Application Scenarios

Sterile filtration of protein solutions and monoclonal antibodies in biopharmaceutical development
Filtration of tissue culture media and additives to prevent microbial contamination
High-temperature liquid filtration in chemical and industrial processes
Removal of particulates from aqueous and mixed solvent samples before HPLC analysis
Filtration of water and chemical reagents requiring low extractables and high purity

Who It Is For

Life-science laboratories conducting protein purification and cell culture work
Pharmaceutical R&D labs requiring low-adsorption filters for drug stability studies
Environmental and food testing labs handling high-temperature or aggressive solvents
OEM filter brands seeking consistent, high-performance membrane substrates
Laboratory distributors sourcing reliable, multi-application membrane filters

Problems It Solves

Low flow rates due to poor wettability or high resistance in hydrophobic membranes
Protein loss during filtration caused by high binding to membrane surfaces
Sample contamination from extractables in low-purity or multi-layer membranes
Inconsistent performance across batches leading to failed method validation
Premature filter failure under high pressure or thermal stress due to weak membrane structure

Data

Specifications

Membrane Material	PES (Polyethersulfone)
Wettability	Hydrophilic
Color	White / Plain
Membrane Format	Disc, Roll, Sheet, Strip, Customizable
Thickness	100±15 μm
Max Operating Pressure	4.2 bar at 23°C
pH Range	6-13
Pore Size	0.1, 0.22, 0.45, 0.65, 0.8, 1.0, 1.2, 5.0 micron
Water Flow Rate	>5 ml/min/cm² (0.1 μm), >8 (0.22 μm), >18 (0.45 μm)
Bubble Point	≥3.4 bar (0.1 μm), ≥2.7 (0.22 μm), ≥1.9 (0.45 μm), ≥1.1 (0.65 μm), ≥0.8 (0.8 μm), ≥0.6 (1.0 μm), ≥0.4 (1.2 μm), ≥0.4 (5.0 μm)
Sterilization Compatibility	Autoclave, Ethylene Oxide, E-Beam, Gamma irradiation
Endotoxin Level	<0.25 Eu/ml
Extractables	<1% (<0.015 mg/cm²)
BSA Protein Binding	<20 μg/cm²

Materials

Polyethersulfone (PES) membrane, modified polymer with asymmetric structure
Hydrophilic surface without surfactant additives
Compatible with standard filter housing materials and assembly methods

Customization Options

Custom membrane formats: Disc, Roll, Sheet, Strip, or bespoke shapes
Custom dimensions and packaging per order
OEM contract manufacturing and private-label packaging available
Sterilization options: Gamma, E-Beam, autoclave, or ethylene oxide
Part number and labeling tailored for client branding

How It Is Made

Manufacturing And Quality Control

Manufacturing Process

Polyethersulfone polymer casting into membrane sheets
Asymmetric structure optimization for high porosity and flow
Membrane die-cutting into disc, roll, sheet, strip, or custom formats
Quality inspection for uniformity and integrity
Sterilization (if specified) via gamma irradiation, E-Beam, autoclave, or ethylene oxide
Packing according to order specifications

Quality Control

Membrane thickness verified within 100±15 μm tolerance
Pore size and bubble point tested per lot
Flow rate measured at 25°C and ΔP = 0.07 MPa
Endotoxin levels confirmed via LAL test using 400 cm²/400 ml S.W.F.I.
Extractables tested to ensure <1% (<0.015 mg/cm²)
BSA protein binding measured to ensure <20 μg/cm²
Lot-to-lot consistency verified through performance testing

Comparison

Compared With The Alternatives

Versus Nylon membranes

PES offers superior chemical resistance and lower extractables, especially in aggressive solvents and high-temperature applications where nylon may degrade.

Versus Cellulose acetate membranes

Use Guide

How To Use It

Select pore size based on particle size: 0.22 μm for sterile filtration, 0.45 μm for routine clarification
Use 0.1 μm for ultrafine particulate removal in sensitive analytical applications
Ensure pH remains within 6-13 range to avoid membrane degradation
For high-temperature applications, confirm operating temperature does not exceed material limits
Sterilize using gamma irradiation, E-Beam, autoclave, or ethylene oxide as required
Avoid exposure to strong oxidizing agents or solvents outside the recommended range
Handle with care during installation to prevent membrane damage

Photos

Product Gallery

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FAQ

Questions Buyers Ask

What is the maximum operating pressure for PES membranes?

Maximum operating pressure is 4.2 bar at 23°C. Exceeding this may compromise membrane integrity.

Can PES membranes be sterilized?

Yes. PES membranes are compatible with autoclave, ethylene oxide, E-Beam, and gamma irradiation sterilization.

What pore sizes are available?

Available pore sizes are 0.1, 0.22, 0.45, 0.65, 0.8, 1.0, 1.2, and 5.0 micron.

Are these membranes suitable for protein filtration?

Yes. PES membranes have low protein adsorption and are ideal for filtering protein solutions and tissue culture media.

How are the filters packed?

Discs are packed in 100, 200, or 50 pieces per pack depending on diameter. Rolls are packed as 1 roll per pack.

Can you supply custom sizes or formats?

Yes. Custom membrane formats including disc, roll, sheet, strip, and bespoke shapes are available through OEM and customization services.