Membrane Filter

CN Membrane Filter

CN Membrane Filters are cellulose nitrate membranes designed for high flow rates in aqueous and organic solvent filtration. They are hydrophilic, compatible with pH 4 to 8, and suitable for particle retention, cell capture, and sterile filtration in HPLC sample preparation, microbiology, and fluid monitoring. The symmetric membrane structure enables rapid flow without compromising retention. Available in disc and sheet formats with customizable options, they support applications requiring low non-specific adsorption and consistent performance across multiple sample types.

High flow rates due to symmetric membrane structure, reducing filtration time for routine and high-volume samples
Hydrophilic surface ensures quick wetting and consistent performance with aqueous and organic solvents
Compatible with pH 4 to 8, making them suitable for a wide range of buffer and mobile phase applications
Available in multiple pore sizes from 0.1 to 8.0 micron, enabling selection for particle retention or cell capture

Key Benefits

What This Product Gives You

High flow rates due to symmetric membrane structure, reducing filtration time for routine and high-volume samples
Hydrophilic surface ensures quick wetting and consistent performance with aqueous and organic solvents
Compatible with pH 4 to 8, making them suitable for a wide range of buffer and mobile phase applications
Available in multiple pore sizes from 0.1 to 8.0 micron, enabling selection for particle retention or cell capture
Disc and sheet formats with customizable options support flexible integration into existing lab workflows

Membrane material: Cellulose Nitrate (CN)
Hydrophilic surface with high flow rates across all pore sizes
Compatible with aqueous solutions (pH 4-8) and several organic solvents
Symmetric membrane structure for consistent flow and retention
Available in disc and sheet formats, with customizable options
Pore sizes from 0.1 to 8.0 micron, covering fine particulate and cell capture needs
Water flow rate at 25°C and 0.07 MPa: up to 480 ml/min/cm² at 8.0 micron
Bubble point values from 0.47 MPa (0.1 μm) to 0.03 MPa (8.0 μm), indicating structural integrity
Sterilization compatible with autoclave, ethylene oxide, E-beam, and gamma irradiation

Where It Is Used

Applications And Buyers

Application Scenarios

Filtering HPLC samples to remove particulates and prevent column frit clogging
Preparing cell culture media and buffers for sterile filtration without protein adsorption
Clarifying aqueous solutions for particle analysis and environmental monitoring
Capturing microorganisms in air and fluid monitoring for QC and compliance testing
Processing solvent-based samples in chemical and pharmaceutical R&D where organic compatibility is required

Who It Is For

Pharmaceutical and biotech labs requiring consistent filtration for HPLC and sample prep
Environmental testing labs performing particle analysis in water and air samples
Food and beverage labs needing sterile filtration of liquids and buffers
Microbiology labs using membrane filters for colony counting and microbial detection
Lab distributors sourcing a versatile membrane filter with multiple pore sizes and formats

Problems It Solves

Slow filtration rates in high-volume sample processing due to low permeability of traditional membranes
Inconsistent wetting in hydrophobic membranes leading to air entrapment and incomplete filtration
Membrane degradation or pH instability in samples outside the 4-8 range
Inadequate particle retention due to oversized pore sizes in low-cost filters
Lack of flexibility in filter format when integrating into automated or custom filtration systems

Data

Specifications

Membrane Material	Cellulose Nitrate
Wettability	Hydrophilic
pH Compatibility	4-8
Membrane Format	Disc, Sheet, Customizable
Membrane Thickness	80±10 μm
Max Operating Pressure	Not specified
Pore Size	0.1, 0.22, 0.45, 0.8, 1.0, 3.0, 5.0, 8.0 micron
Water Flow Rate (25°C, 0.07 MPa)	≥7 ml/min/cm² (0.1 μm) to ≥480 ml/min/cm² (8.0 μm)
Bubble Point	≥0.47 MPa (0.1 μm) to ≥0.03 MPa (8.0 μm)
Sterilization Compatibility	Autoclave, Ethylene Oxide, E-beam, Gamma irradiation
Filter Surface	White, Grid/Plain
Packing	200 pcs/pk (13 mm, 25 mm), 100 pcs/pk (47 mm, 90 mm, 142 mm), 50 pcs/pk (142 mm), 25 pcs/pk (293 mm)

Materials

Cellulose Nitrate membrane
White or grid-patterned filter surface

Customization Options

Available in disc and sheet formats with customizable dimensions and shapes
Options for surface pattern: plain or grid
Sterile and non-sterile versions available
Private-label printing and packaging available through the Microlab OEM division
OEM contract manufacturing and membrane die-cutting services offered

How It Is Made

Manufacturing And Quality Control

Manufacturing Process

Membrane die-cutting from cellulose nitrate sheet stock
Precision cutting to disc or sheet format based on order
Customization of size, shape, and surface pattern upon request
Sterilization via autoclave, ethylene oxide, E-beam, or gamma irradiation as specified
Packing according to order: 200 pcs/pk (13 mm, 25 mm), 100 pcs/pk (47 mm, 90 mm, 142 mm), 50 pcs/pk (142 mm), 25 pcs/pk (293 mm)

Quality Control

Membrane thickness verified at 80±10 μm
Pore size confirmed against specified values
Bubble point tested to ensure structural integrity
Wettability and flow rate validated at 25°C and 0.07 MPa
Sterilization method verified for compatibility with membrane integrity

Comparison

Compared With The Alternatives

Versus Mixed cellulose ester (MCE) membranes

CN membranes offer higher flow rates and better compatibility with organic solvents, but MCE may have lower protein adsorption in some biological applications

Versus Non-sterile filters

Sterile versions are available with gamma or E-beam sterilization, reducing the risk of contamination in sensitive applications

Use Guide

How To Use It

Select pore size based on particle or cell size: 0.22 μm for sterile filtration, 0.45 μm for routine clarification, 0.8 μm and above for larger particles
Use for aqueous samples within pH 4 to 8; avoid use in strongly acidic or basic conditions
Ensure proper wetting by pre-rinsing with water or compatible solvent before filtration
For sterile applications, use the sterile version and handle under clean conditions
Do not exceed recommended flow rates to prevent membrane damage or bypass
Dispose of after single use to avoid carry-over or contamination

Photos

Product Gallery

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FAQ

Questions Buyers Ask

What is the maximum pH range for CN membrane filters?

The CN membrane is compatible with pH 4 to 8. Use alternative membranes for samples outside this range.

Can CN membranes be used for organic solvent filtration?

Yes, CN membranes are compatible with hydrocarbons and several organic solvents, but avoid strong acids or bases.

What is the difference between the sterile and non-sterile versions?

Sterile versions are treated with gamma irradiation or E-beam and are suitable for sterile filtration. Non-sterile versions are not sterilized and must be sterilized before use.

Are the filters available in different sizes?

Yes, available in diameters of 13 mm, 25 mm, 47 mm, 90 mm, 142 mm, and 293 mm with varying packing quantities.

Can I get custom sizes or shapes?

Yes, the membrane format is customizable. Contact the OEM division for custom die-cutting and sizing.

What sterilization methods are compatible?

CN membranes are compatible with autoclave, ethylene oxide, E-beam, and gamma irradiation.