Membrane Filter

CA Membrane Filter

The CA Membrane Filter is an unsupported, hydrophilic membrane made from pure cellulose acetate, designed for applications requiring minimal protein binding and high throughput. It maintains dimensional stability and provides consistent flow rates across a range of pore sizes from 0.1 to 5.0 micron. The membrane is suitable for protein and enzyme filtration, sterilization of biological fluids, and tissue culture media preparation, where recovery of active components is critical. Its low binding properties reduce sample loss during filtration, and its chemical resistance across pH 4 to 8 ensures compatibility with common laboratory buffers and solutions.

Unsupported cellulose acetate membrane provides naturally low protein binding, improving recovery of sensitive biomolecules
High flow rates across all pore sizes reduce filtration time and the need for frequent filter changes
Dimensional stability ensures consistent performance under standard operating conditions
Chemical resistance from pH 4 to 8 allows use with a wide range of aqueous and buffer-based solutions

Key Benefits

What This Product Gives You

Unsupported cellulose acetate membrane provides naturally low protein binding, improving recovery of sensitive biomolecules
High flow rates across all pore sizes reduce filtration time and the need for frequent filter changes
Dimensional stability ensures consistent performance under standard operating conditions
Chemical resistance from pH 4 to 8 allows use with a wide range of aqueous and buffer-based solutions
Available in disc, roll, sheet, strip, and customizable formats to match diverse lab and industrial filtration setups

Membrane material: Cellulose acetate, unsupported
Wettability: Hydrophilic
Colour: White, plain surface
Available formats: Disc, Roll, Sheet, Strip, Customizable
Thickness: 100±15 μm
Maximum operating pressure: 4.2 bar at 23°C
pH range: 4 to 8
Pore sizes: 0.1, 0.22, 0.45, 0.65, 0.8, 1.0, 1.2, 5.0 micron
Water flow rate at 25°C and Δp = 0.07 MPa: >5 ml/min/cm² (0.1 μm), >8 (0.22 μm), >18 (0.45 μm)
Bubble point: ≥3.4 bar (0.1 μm), ≥2.7 (0.22 μm), ≥1.9 (0.45 μm), ≥1.1 (0.65 μm), ≥0.8 (0.8 μm), ≥0.6 (1.0 μm), ≥0.4 (1.2 μm), ≥0.4 (5.0 μm)
Sterilization compatibility: Autoclave, Ethylene Oxide, E-Beam, Gamma irradiation

Where It Is Used

Applications And Buyers

Application Scenarios

Filtration of protein solutions and enzyme preparations where minimal binding ensures high recovery
Sterilization of biological fluids and tissue culture media without loss of activity
Preparation of diagnostic cytology samples requiring low adsorption of cellular components
Receptor binding studies where sample integrity and minimal matrix interference are essential
High-volume processing of biological samples in biotechnology and life-science laboratories

Who It Is For

Life-science research labs conducting protein purification and enzyme assays
Biopharmaceutical QC labs requiring consistent recovery of therapeutic proteins
Tissue culture and cell biology labs preparing sterile media with minimal component loss
Diagnostic labs processing biological samples for cytology and immunoassays
OEM partners needing customizable membrane formats for integrated filtration systems

Problems It Solves

Low recovery of proteins due to high binding on conventional membranes during filtration
Frequent filter clogging caused by poor flow rates in protein-rich samples
Sample loss during sterilization of sensitive biological fluids due to adsorption
Inconsistent results in receptor binding studies from variable membrane performance
Limited flexibility in membrane format when scaling up from lab to production filtration

Data

Specifications

Membrane Material	Cellulose Acetate
Wettability	Hydrophilic
Colour	White / Plain
Format	Disc, Roll, Sheet, Strip, Customizable
Thickness	100±15 μm
Max Operating Pressure	4.2 bar at 23°C
pH Range	4-8
Pore Size	0.1, 0.22, 0.45, 0.65, 0.8, 1.0, 1.2, 5.0 micron
Water Flow Rate	>5 ml/min/cm² (0.1 μm), >8 (0.22 μm), >18 (0.45 μm)
Bubble Point	≥3.4 bar (0.1 μm), ≥2.7 (0.22 μm), ≥1.9 (0.45 μm), ≥1.1 (0.65 μm), ≥0.8 (0.8 μm), ≥0.6 (1.0 μm), ≥0.4 (1.2 μm), ≥0.4 (5.0 μm)
Sterilization Compatibility	Autoclave, Ethylene Oxide, E-Beam, Gamma irradiation

Materials

Pure cellulose acetate membrane
Unsupported construction for minimal matrix interference

Customization Options

Custom membrane formats including discs, rolls, sheets, strips, and bespoke shapes
Custom packaging quantities and configurations
Private-label printing and branding available through the Microlab OEM division
OEM contract manufacturing and membrane die-cut and packing services for filter brands

How It Is Made

Manufacturing And Quality Control

Manufacturing Process

Membrane die-cutting from raw cellulose acetate sheets
Precision sizing and formatting into discs, rolls, sheets, strips, or custom shapes
Quality inspection of pore uniformity and surface integrity
Sterilization (if specified) via gamma irradiation or other compatible methods
Packing according to order format and quantity

Quality Control

Pore size verified against specified values using bubble point and flow rate testing
Surface uniformity and thickness checked across production batches
Sterilization validation performed for gamma-sterilized variants
Visual inspection for defects, tears, or contamination before packing

Comparison

Compared With The Alternatives

Versus Nylon membranes

CA membrane has lower protein binding than nylon, making it better for protein recovery in sensitive applications

Versus Mixed cellulose ester (MCE)

CA has higher dimensional stability and lower binding than MCE, reducing sample loss and filter deformation

Versus PTFE membranes

CA is hydrophilic and suitable for aqueous samples without pre-wetting, unlike PTFE which requires wetting for water-based applications

Use Guide

How To Use It

Select pore size based on particle or molecule size: 0.22 μm for sterilization, 0.45 μm for routine clarification, 0.1 μm for high-resolution filtration
Use only within pH 4 to 8 to maintain membrane integrity and performance
For protein solutions, choose CA over other membranes to minimize binding and maximize recovery
Pre-wet hydrophilic CA membranes with water or buffer before use to ensure even flow
Do not exceed 4.2 bar at 23°C to avoid membrane damage or failure
For gamma-sterile variants, store in sealed packaging until use to maintain sterility

Photos

Product Gallery

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FAQ

Questions Buyers Ask

Can CA membranes be used for sterilizing water-based solutions?

Yes. CA is hydrophilic and compatible with water-based solutions. It can be used for sterilization at 0.22 μm pore size, provided pH is between 4 and 8.

What is the maximum pressure the CA membrane can withstand?

Maximum operating pressure is 4.2 bar at 23°C. Exceeding this may cause membrane deformation or failure.

Are CA membranes suitable for protein filtration?

Yes. CA membranes have naturally low protein binding, making them ideal for protein and enzyme filtration where recovery is critical.

Do you offer gamma-sterile CA membranes?

Yes. Gamma-sterile versions are available, such as M47CA022S and M47CA045S, packed in 100 pieces per pack.

Can I get CA membranes in custom sizes or formats?

Yes. Custom formats including discs, rolls, sheets, strips, and bespoke shapes are available through the Microlab OEM division.