Ionrganic Chemical Base SPE Column product photo 1

SPE Column

Ionrganic Chemical Base SPE Column

Ionrganic Chemical Base SPE Columns are solid phase extraction columns designed for the selective isolation and purification of polar and structurally similar compounds from complex matrices. Available in four sorbent types-unbounded silica gel, Florisil pesticide grade, alumina (acidic, neutral, basic), and graphitized carbon black-these columns support high sample loadability and strong retention for polar analytes. Each sorbent is tailored to specific applications, including pesticide residue analysis, mycotoxin detection, biomolecule separation, and environmental contaminant screening. The manufacturing process minimizes variability to improve recovery and cleanup efficiency.

Four sorbent types cover polar, non-polar, and structurally similar compound extraction across biological, food, environmental, and cosmetic matrices
High sample loadability enables processing of larger volumes without breakthrough
Minimized variability in manufacturing improves recovery and reproducibility in method validation
Column sizes available in 1 ml, 3 ml, 6 ml, and 10 ml volumes to match sample volume and matrix complexity

Key Benefits

What This Product Gives You

Four sorbent types cover polar, non-polar, and structurally similar compound extraction across biological, food, environmental, and cosmetic matrices
High sample loadability enables processing of larger volumes without breakthrough
Minimized variability in manufacturing improves recovery and reproducibility in method validation
Column sizes available in 1 ml, 3 ml, 6 ml, and 10 ml volumes to match sample volume and matrix complexity
Sorbents selected for specific retention mechanisms: silica for polar compounds, Florisil for pesticides, alumina for amines, and GCB for pigments and organochlorines

Four sorbent types: unbounded silica gel, Florisil pesticide grade, alumina (ALA, ALN, ALB), graphitized carbon black
Available in 1 ml, 3 ml, 6 ml, and 10 ml column volumes
Unbounded silica gel: surface area 480 m²/g, particle size 40-75 µm, pore size 70 Å
Florisil: particle size 150-250 µm, highly porous and polar for pesticide retention
Alumina: pH 4.0 (ALA), 7.0 (ALN), 9.5 (ALB), suitable for high pH stability
Graphitized carbon black: surface area 100 m²/g, particle size 100-300 mesh, nonporous sheet-like structure
Designed for high sample loadability and efficient cleanup
Manufactured to minimize variability for consistent performance

Where It Is Used

Applications And Buyers

Application Scenarios

Extracting polar drugs and metabolites from biological fluids in pharmaceutical QC
Purifying mycotoxins such as fumonisins from food samples using silica or Florisil
Removing pigments from vegetables and fruits prior to pesticide analysis with GCB
Isolating aromatic amines and phenols from environmental water samples using alumina
Cleaning up complex matrices before GC or LC-MS analysis of organochlorine pesticides

Who It Is For

Pharmaceutical and clinical laboratories conducting residue analysis in biological samples
Food safety labs testing for mycotoxins, pesticides, and preservatives in crops and processed foods
Environmental testing labs analyzing pollutants and herbicides in water and soil
Cosmetic and personal care product labs screening for pesticide residues and synthetic pigments
Contract testing labs requiring consistent recovery and low variability across batches

Problems It Solves

Low recovery of polar compounds due to weak retention on non-polar sorbents
Matrix interference from pigments or lipids in food and biological samples
Breakthrough of target analytes during high-volume sample loading
Inconsistent recovery between batches due to sorbent variability
Need for multiple sorbent types across different sample types, increasing inventory complexity

Data

Specifications

Sorbent Type	Unbounded Silica Gel, Florisil Pesticide Grade, Alumina (ALA, ALN, ALB), Graphitized Carbon Black
Column Volume	1 ml, 3 ml, 6 ml, 10 ml
Surface Area	480 m²/g (Silica), >150 m²/g (Alumina), 100 m²/g (GCB)
Particle Size	40-75 µm (Silica), 150-250 µm (Florisil), 100-300 mesh (GCB)
Pore Size	70 Å (Silica)
pH Stability	ALA: 4.0, ALN: 7.0, ALB: 9.5
Applications	Drug metabolites, pesticides, mycotoxins, biomolecules, pigments, organochlorines
Manufacturing Process	Minimizes variability to improve recovery and cleanup
Packaging	100 pcs/pk (1 ml), 50 pcs/pk (3 ml, 6 ml), 30 pcs/pk (6 ml, 10 ml)

Materials

Unbounded silica gel sorbent
Synthetic magnesium-silica (Florisil)
Alumina (acidic, neutral, basic formulations)
Graphitized carbon black with aromatic ring structure

Customization Options

Choice of four sorbent types for tailored extraction of polar, non-polar, or structurally similar compounds
Available in 1 ml, 3 ml, 6 ml, and 10 ml column volumes to suit sample volume and matrix
OEM private-label packaging and labeling available through the Microlab OEM division
Custom packaging configurations (e.g., 50 pcs/pk, 30 pcs/pk) can be arranged for bulk orders

How It Is Made

Manufacturing And Quality Control

Manufacturing Process

Sorbent preparation and particle size control
Column filling with precise mass and volume calibration
Compression and sealing of the column housing
Quality inspection of fill weight and integrity
Packing in specified quantities per package (100, 50, or 30 pcs/pk)

Quality Control

Sorbent batch consistency verified before column filling
Fill weight and column volume checked against specification
Integrity test performed on filled columns to prevent leakage
Recovery and cleanup performance monitored across production batches
Labeling verified to match sorbent type, volume, and package count

Comparison

Compared With The Alternatives

Versus Silica-based SPE columns with bonded phases

Unbounded silica gel offers stronger polarity and higher retention for polar compounds but may have lower stability at extreme pH compared to bonded phases.

Versus Florisil columns from other suppliers

Microlab's Florisil is pesticide grade, suitable for multiresidual analysis and aligned with EPA 608 and NY/T 761 methods.

Versus Generic carbon black sorbents

Graphitized carbon black has a nonporous, sheet-like structure that enables faster extraction and higher capacity than porous carbon sorbents.

Versus Single-sorbent SPE kits

The four-sorbent range allows one supplier to cover multiple extraction needs, reducing the number of vendors and inventory complexity.

Use Guide

How To Use It

Select sorbent based on analyte polarity: silica for polar compounds, Florisil for pesticides, alumina for amines, GCB for pigments and organochlorines
Choose column volume based on sample volume: 1 ml for small samples, 6-10 ml for large or complex matrices
Condition the column with appropriate solvent before sample loading to ensure proper sorbent activation
Load sample at a controlled flow rate to avoid breakthrough
Wash with solvent to remove interferences, then elute analytes with a strong solvent
Use method-specific protocols such as EPA 608, GB 5009.265-2016, or NY/T 1756-2012 for regulatory compliance
Store columns in a dry, cool place to prevent sorbent degradation

FAQ

Questions Buyers Ask

Which sorbent should I use for extracting polar drugs from plasma?

Use unbounded silica gel for strong retention of polar compounds. It has the highest polarity among normal phase sorbents and is effective for drugs and metabolites with similar structures.

Can I use Florisil for organophosphorus pesticide analysis?

Yes. Florisil is effective for chlorine-, nitrogen-, and phosphorus-containing pesticides and is used in EPA 608 and NY/T 761 methods for multiresidue analysis.

What is the difference between ALA, ALN, and ALB alumina?

ALA is acidic (pH 4.0), ALN is neutral (pH 7.0), and ALB is basic (pH 9.5). Choose based on analyte stability and interaction with the sorbent surface.

How do I handle high-volume samples?

Use larger column volumes (6 ml or 10 ml) or graphitized carbon black (GCB), which has higher extraction speed and capacity than silica-based sorbents.

Are these columns compatible with GC and LC-MS?

Yes. The columns are designed for use in sample preparation prior to GC, LC, and LC-MS analysis, with low carryover and high recovery.

Can you supply these under our private label?

Yes. The Microlab OEM division offers private-label packaging, custom labeling, and bulk supply arrangements for SPE columns.

What is the packaging for each column size?

1 ml: 100 pcs/pk; 3 ml and 6 ml: 50 pcs/pk; 10 ml: 30 pcs/pk. Packaging is based on column volume and usage frequency.