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SPE Column

Empty SPE Cartridge

Empty SPE cartridges are straight-walled syringe barrel tubes made from polypropylene, designed for customers to pack with custom sorbents. Each cartridge includes two ultrapure sintered PE frits to maintain high sensitivity in analytical results. Available in eight volumes from 1 mL to 300 mL, they support a wide range of sample preparation needs in pharmaceutical, environmental, food and beverage, and life-science testing.

  • Straight-walled polypropylene barrels allow consistent packing and predictable flow dynamics during SPE procedures
  • Two ultrapure sintered PE frits reduce extractables and maintain high sensitivity in low-level detection
  • Eight volume options from 1 mL to 300 mL provide flexibility across small-scale screening and large-volume industrial applications
  • Standardised geometry enables consistent performance when using custom sorbents across multiple batches
Key Benefits

What This Product Gives You

  • Straight-walled polypropylene barrels allow consistent packing and predictable flow dynamics during SPE procedures
  • Two ultrapure sintered PE frits reduce extractables and maintain high sensitivity in low-level detection
  • Eight volume options from 1 mL to 300 mL provide flexibility across small-scale screening and large-volume industrial applications
  • Standardised geometry enables consistent performance when using custom sorbents across multiple batches
  • No pre-packed sorbent means no waste of expensive materials and full control over sorbent selection and loading
  • Straight-walled syringe barrel tubes made from polypropylene
  • Two ultrapure sintered PE frits per cartridge for consistent flow and low extractables
  • Eight volume sizes: 1 mL, 3 mL, 6 mL, 12 mL, 20 mL, 30 mL, 60 mL, 300 mL
  • Compatible with standard syringe filter fittings and SPE manifolds
  • Designed for manual or automated packing with custom sorbents
  • No pre-loaded sorbent allows full control over bed volume and packing density
Where It Is Used

Applications And Buyers

Application Scenarios

  • Preparing environmental water samples for trace pesticide analysis using custom sorbents
  • Processing pharmaceutical bulk drug samples with tailored sorbents for targeted analyte isolation
  • Handling high-volume food and beverage samples requiring large bed volumes for residue extraction
  • Supporting contract research organisations that need to test multiple sorbent types across a single sample matrix
  • Enabling lab-scale development of SPE methods before scaling to pre-packed commercial cartridges

Who It Is For

  • Pharmaceutical R&D labs developing custom SPE methods with proprietary sorbents
  • Environmental testing labs that use different sorbents for varying contaminant classes
  • Food and beverage labs preparing complex matrices with variable analyte profiles
  • Contract research organisations running multiple SPE workflows under different client specifications
  • Lab distributors and OEM filter brands that require blank cartridges for private-label packing

Problems It Solves

  • High cost of pre-packed SPE cartridges when testing multiple sorbents or small batches
  • Inconsistent performance when using non-standard or custom sorbent bed heights in commercial cartridges
  • Limited volume options in commercial SPE columns that don't match the scale of a specific method
  • Risk of contamination from residual solvents or additives in pre-packed sorbents
  • Inflexibility when switching between sorbent types without changing cartridge geometry or vendor
Data

Specifications

Volume1 mL, 3 mL, 6 mL, 12 mL, 20 mL, 30 mL, 60 mL, 300 mL
MaterialPolypropylene barrel, PE frits
Frits2 x sintered PE frits
Packing100/pk (1-60 mL), 50/pk (20-60 mL), 10/pk (300 mL)
GeometryStraight-walled syringe barrel
CompatibilityStandard syringe filter fittings and SPE manifolds

Materials

  • Polypropylene barrel
  • Sintered PE frits

Customization Options

  • Available in eight volumes from 1 mL to 300 mL
  • OEM contract manufacturing and private-label packing available through the Microlab OEM division
  • Custom packaging options for bulk orders
  • Support for lab-specific sorbent loading protocols via OEM services
How It Is Made

Manufacturing And Quality Control

Manufacturing Process

  • Manufacture of ultrapure sintered PE frits
  • Assembly of frits into the barrel
  • Inspection of frit integrity and barrel wall uniformity
  • Packing in specified quantities per order

Quality Control

  • Barrel wall thickness and straightness verified during moulding
  • Frits inspected for porosity and structural integrity before assembly
  • Final assembly checked for correct frit placement and barrel alignment
  • Packing verified against order quantity and volume specification
Comparison

Compared With The Alternatives

Versus Pre-packed SPE cartridges

Empty cartridges eliminate waste from unused sorbent and allow full control over sorbent type, bed height, and packing method

Versus Cartridges with non-sintered frits

Sintered PE frits provide better mechanical stability and lower extractables, which is critical for high-sensitivity analysis

Versus Cartridges with tapered walls

Straight-walled barrels ensure consistent packing and predictable flow, reducing variability in extraction efficiency

Versus Cartridges with plastic frits from other materials

Sintered PE frits offer superior chemical resistance and lower extractables compared to some alternative frit materials

Use Guide

How To Use It

  • Select the cartridge volume based on sample size and required sorbent bed depth
  • Clean the cartridge and frits with appropriate solvent before packing with sorbent
  • Load sorbent uniformly into the barrel using a funnel or automated system
  • Ensure the sorbent bed is compacted to the desired density without over-compression
  • Use the cartridge immediately after packing to avoid contamination or sorbent degradation
  • Follow standard SPE protocol: conditioning, sample loading, washing, and elution
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FAQ

Questions Buyers Ask

What is the difference between these empty SPE cartridges and pre-packed ones?

These are blank cartridges without any sorbent. You pack them with your own sorbent, which allows full control over material type, bed height, and packing method.

Can I use these cartridges with any sorbent type?

Yes. The polypropylene barrel and PE frits are compatible with most common SPE sorbents, including silica-based, ion-exchange, and reversed-phase materials.

What is the packing quantity for each size?

1 mL to 60 mL: 100 per pack. 20 mL to 60 mL: 50 per pack. 300 mL: 10 per pack.

Are the frits sintered or bonded?

The frits are sintered PE, which provides high chemical resistance and low extractables for sensitive analyses.

Can I get these cartridges with my own brand name?

Yes. The Microlab OEM division offers private-label packing and contract manufacturing for empty SPE cartridges.

What is the maximum operating pressure?

The cartridges are designed for standard SPE pressures. No maximum pressure is specified in the source facts.

Get A Quote For Empty SPE Cartridge

Tell us the membrane, pore size, diameter and quantity you need, or describe the sample and we will specify it.