Syringe Filter

Vent Filter

The 50mm Vent Filter is designed for venting and liquid filtration in bioreactors, fermenters, and sterile processing systems. It removes microorganisms, particles, precipitates, and undissolved powders larger than the nominal pore size of 0.22 or 0.45 micron. The filter features a low hold-up volume and minimal particle shedding, making it suitable for critical applications in pharmaceutical and biotechnology processes.

50mm diameter provides large surface area for high throughput and increased air flow rates
Thermal bonding sealing without adhesives reduces extractables and maintains integrity during sterilization
Reusable and autoclavable up to three cycles of 30 minutes at 123℃, supporting repeated use in sterile processes
Low hold-up volume minimizes sample loss and product carry-over in sensitive bioprocesses

Key Benefits

What This Product Gives You

50mm diameter provides large surface area for high throughput and increased air flow rates
Thermal bonding sealing without adhesives reduces extractables and maintains integrity during sterilization
Reusable and autoclavable up to three cycles of 30 minutes at 123℃, supporting repeated use in sterile processes
Low hold-up volume minimizes sample loss and product carry-over in sensitive bioprocesses
Minimal particle shedding ensures clean filtrate, reducing contamination risk in sterile environments

Five membrane options: Nylon, PTFE, Hydrophilic PTFE, CA, PES, PVDF, Hydrophilic PVDF
Diameter of 50 mm with filtration area ≥0.021 cm²
Pore sizes of 0.22 and 0.45 micron available
Stepped hose barb inlet (7-13 mm) with 6:100 luer slip outlet for flexible connection
Maximum operating pressure: 3.5 bar at 23℃ for liquids, 3 bar at 23℃ for air/gas; 3.0 bar at 60℃ for liquids, 2.5 bar at 60℃ for air/gas
Sterilized by EO or three autoclave cycles of 30 minutes at 123℃

Where It Is Used

Applications And Buyers

Application Scenarios

Venting bioreactors and fermenters during sterile culture processes
Filtering air and gas streams in sterile processing lines to prevent microbial ingress
Sterilizing liquid feeds before introduction into closed bioprocess systems
Removing particulates and microorganisms from buffer solutions in biotechnology workflows
Supporting reusable filtration in high-volume bioprocessing where cost and consistency matter

Who It Is For

Pharmaceutical and biotechnology laboratories requiring sterile filtration in bioreactor systems
Bioprocessing teams using reusable filtration components in fermenter vent lines
R&D labs developing sterile cell culture and fermentation protocols
Contract manufacturers running high-throughput sterile processes with strict contamination control
Lab distributors sourcing reusable, autoclavable filters with broad chemical resistance

Problems It Solves

Microbial contamination entering bioreactors through unfiltered vent lines
High hold-up volume in filters causing product loss in small-scale bioprocesses
Particle shedding from filters contaminating sensitive cell cultures or protein solutions
Frequent filter replacement due to poor reusability in sterile environments

Data

Specifications

Filter Media	Nylon, PTFE, Hydrophilic PTFE, CA, PES, PVDF, Hydrophilic PVDF
Housing	PP
Diameter	50 mm
Filtration Area	≥0.021 cm²
Pore Size	0.22, 0.45 micron
Sealing Technology	Thermal bonding, No adhesives
Inlet/Outlet	7-13 mm stepped hose barb with 6:100 luer slip
Max Operating Pressure	3.5 bar at 23 C (liquid), 3.0 bar at 60 C (liquid), 3.0 bar at 23 C (air/gas), 2.5 bar at 60 C (air/gas)
Sterilization	EO or 3 autoclave cycles of 30 min at 123℃
Packing	25 pcs per pack

Materials

Membrane selected per application: Nylon, PTFE, Hydrophilic PTFE, CA, PES, PVDF, Hydrophilic PVDF

Customization Options

OEM printing and private-label packing through the Microlab OEM division
OEM contract manufacturing and membrane die-cut and packing for filter brands
Part number selection based on membrane type, pore size, and packing

How It Is Made

Manufacturing And Quality Control

Manufacturing Process

Membrane die cutting to size
Connection port formation with stepped hose barb and luer slip
Sterilization by EO or three autoclave cycles of 30 minutes at 123℃
Packing at 25 pieces per pack

Quality Control

Membrane and housing inspected before assembly
Sealing integrity tested under maximum operating pressure
Pore size and membrane type verified against part number
Sterilization validation performed per EO or autoclave cycle specification

Comparison

Compared With The Alternatives

Versus Solvent-bonded filters

Thermal bonding eliminates adhesive in the flow path, reducing extractables and improving compatibility with sensitive bioprocesses

Versus Single-use vent filters

Reusable design supports multiple autoclave cycles, reducing consumable cost over time in high-volume bioprocessing

Versus Smaller diameter filters

50mm diameter provides larger filtration area and higher throughput, reducing pressure drop during high air flow

Versus Filters with adhesive seals

No adhesives used in sealing ensures no leaching during repeated sterilization, maintaining filter integrity

Use Guide

How To Use It

Select membrane based on fluid compatibility: PTFE and PVDF for aggressive solvents, PES and CA for aqueous solutions, Nylon for mixed phases
Use 0.22 micron for sterilizing filtration of liquids and gases, 0.45 micron for particulate removal in non-sterile applications
Connect the stepped hose barb (7-13 mm) to tubing and ensure a secure fit before use
Sterilize by EO or three autoclave cycles of 30 minutes at 123℃ before first use and after each cycle
Do not exceed 3.5 bar at 23℃ for liquids or 3.0 bar at 60℃; monitor pressure during operation

Photos

Product Gallery

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FAQ

Questions Buyers Ask

What membranes are available for the 50mm Vent Filter?

Available membranes are Nylon, PTFE, Hydrophilic PTFE, CA, PES, PVDF, and Hydrophilic PVDF

What is the maximum operating pressure?

For liquids: 3.5 bar at 23℃ and 3.0 bar at 60℃. For air and gas: 3.0 bar at 23℃ and 2.5 bar at 60℃

How is the filter sealed?

The filter uses thermal bonding with no adhesives, which reduces extractables and improves compatibility with sterile processes

What is the packing quantity?

Each pack contains 25 pieces. Part numbers are assigned per membrane type and pore size

Can I get these under my own brand?

Yes. The Microlab OEM division offers private-label printing and packing, OEM contract manufacturing, and membrane die-cut and packing