Syringe Filter

Allfil Syringe Filter

Allfil is a syringe filter designed for routine and demanding sample preparation in HPLC, GC, and biological analysis. The injection-moulded sealing withstands 6 bar at 23 C, making it suitable for viscous or particle-laden samples. The filter supports nine membrane types, covering aqueous, organic, and protein-containing matrices, with pore sizes from 0.1 to 5.0 micron. A consistent geometry across all sizes simplifies method transfer and reduces inventory complexity.

Single-layer membrane construction minimises dissolution and extractables, reducing ghost peaks in gradient HPLC runs
Injection-moulded sealing provides a 6 bar burst pressure at 23 C, preventing housing failure during high-pressure filtration
Three housing diameters (13 mm, 25 mm, 30 mm) allow selection based on sample volume and particle load
Nine membrane options cover diverse sample chemistries including aggressive solvents, aqueous matrices, and biological samples

Key Benefits

What This Product Gives You

Single-layer membrane construction minimises dissolution and extractables, reducing ghost peaks in gradient HPLC runs
Injection-moulded sealing provides a 6 bar burst pressure at 23 C, preventing housing failure during high-pressure filtration
Three housing diameters (13 mm, 25 mm, 30 mm) allow selection based on sample volume and particle load
Nine membrane options cover diverse sample chemistries including aggressive solvents, aqueous matrices, and biological samples
Consistent geometry across sizes supports method transfer without revalidation when switching between diameters

Nine membrane options: Nylon, PTFE, Hydrophilic PTFE, MCE, RC, CA, PES, PVDF, Hydrophilic PVDF
Three housing diameters: 13 mm, 25 mm, 30 mm, with filtration areas of 0.92 cm², 2.98 cm², and 4.9 cm² respectively
Pore sizes from 0.1 to 5.0 micron, including 0.22 and 0.45 micron for routine HPLC clean-up
Female luer lock inlet and male luer slip outlet for compatibility with standard syringes
Maximum operating pressure of 6 bar at 23 C, achieved through injection-moulded sealing

Where It Is Used

Applications And Buyers

Application Scenarios

Filtering mobile phases and standards before HPLC and GC injection to prevent column contamination
Preparing protein-rich samples for chromatography without membrane adsorption or sample loss
Handling viscous or particle-laden samples such as crude extracts, cell lysates, or environmental suspensions
Routine sample clean-up in pharmaceutical QC labs where method reproducibility is critical
Filtration of food and beverage samples containing oils, particulates, or high-solids content

Who It Is For

Pharmaceutical and biotech laboratories requiring low extractables for HPLC and UHPLC methods
Environmental and food testing labs processing mixed aqueous and organic samples with variable particle loads
Contract testing organisations managing multiple methods across different instruments and sample types
Lab distributors seeking a single supplier for multiple membrane types and housing sizes with consistent packaging

Problems It Solves

Ghost peaks in gradient HPLC runs caused by extractables from multi-layer or solvent-bonded filters
Filter housing bursting under pressure when processing viscous or high-particulate samples
Inconsistent filtration performance due to variable membrane contact area across different housing sizes
Inventory complexity from sourcing multiple filter geometries and membrane types from separate suppliers
Sample loss or adsorption in biological matrices due to high retention on non-optimized membranes

Data

Specifications

Filter Media	Nylon, PTFE, Hydrophilic PTFE, MCE, RC, CA, PES, PVDF, Hydrophilic PVDF
Housing	PP
Diameter	13 mm, 25 mm, 30 mm
Filtration Area	0.92 cm² (13 mm), 2.98 cm² (25 mm), 4.9 cm² (30 mm)
Pore Size	0.1, 0.22, 0.45, 1.0, 3.0, 5.0 micron
Sealing Technology	Injection molding
Max Operating Pressure	6 bar at 23 C
Inlet / Outlet	Female luer lock / male luer slip
Packing	100 pcs per pack

Materials

Membrane selected per application: Nylon, PTFE, Hydrophilic PTFE, MCE, RC, CA, PES, PVDF, Hydrophilic PVDF

Customization Options

Choice of nine membranes across 0.1 to 5.0 micron pore sizes
Three housing diameters: 13 mm, 25 mm, 30 mm
OEM printing and private-label packing available through the Microlab OEM division
OEM contract manufacturing, membrane die-cut and packing services for filter brands

How It Is Made

Manufacturing And Quality Control

Manufacturing Process

Membrane die cutting to precise dimensions
Injection-moulded sealing of the membrane into the housing
Part number and membrane type printed on each housing
Packing at 100 pieces per pack

Quality Control

Membrane and housing inspected before assembly
Sealing integrity tested to 6 bar at 23 C
Pore size and membrane type verified against the printed part number

Comparison

Compared With The Alternatives

Versus Multi-layer syringe filters

The single-layer membrane reduces dissolution and extractables, which is critical for sensitive HPLC methods. Multi-layer filters add prefilter capacity but introduce more contact material into the flow path.

Versus Solvent-bonded housings

Injection-moulded sealing avoids adhesive residues in the flow path and provides a higher burst pressure rating.

Versus Filters with inconsistent geometries

Allfil's consistent design across 13 mm, 25 mm, and 30 mm sizes enables method transfer without revalidation.

Versus Reusable filter holders

Single-use filters eliminate carry-over risk and cleaning validation burden, especially in high-throughput labs.

Use Guide

How To Use It

Select membrane based on sample chemistry: PTFE and PP for aggressive solvents, PES and MCE for aqueous samples, Nylon and RC for mixed phases
Use 13 mm for sample volumes under 5 mL, 25 mm for moderate loads, and 30 mm for high-volume or high-particulate samples
Choose 0.45 micron for routine HPLC clean-up and 0.22 micron for sterile-grade or ultra-fine filtration
Attach syringe to female luer lock inlet, expel air, and filter at a steady rate
Discard the first few drops if the method is sensitive to membrane wetting solvent
Do not exceed 6 bar at 23 C; if pressure rises rapidly, switch to a larger diameter or coarser pore size

Photos

Product Gallery

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FAQ

Questions Buyers Ask

Which membrane should I use for organic mobile phase filtration?

Use hydrophobic PTFE or PP for aggressive organic solvents. Hydrophilic PTFE and PES are suitable for mixed aqueous-organic phases.

What is the difference between 13 mm, 25 mm, and 30 mm filters?

The 13 mm filter has 0.92 cm² area and suits small volumes. The 25 mm has 2.98 cm² and handles moderate loads. The 30 mm has 4.9 cm² and is best for high-volume or high-particulate samples.

What is the maximum pressure the filter can handle?

Maximum operating pressure is 6 bar at 23 C. This is achieved through injection-moulded sealing, not solvent bonding.

Can I use Allfil for biological samples like cell culture supernatant?

Yes. The single-layer membrane and low retention design are suitable for biological matrices, especially with PES, PTFE, or PVDF membranes.

How are the filters packed?

All filters are packed in 100 pieces per pack. Each housing is printed with the membrane type and pore size for immediate identification.

Do you offer private-label or OEM options?

Yes. The Microlab OEM division provides OEM contract manufacturing, membrane die-cut and packing, and private-label printing.