Syringe Filter

Sterifil Syringe Filter

Sterifil™ syringe filters are designed for applications requiring sterile filtration and low extractables. Each filter is individually packed and sterilized by gamma radiation, ensuring a contamination-free start for sensitive analytical and biotechnological workflows. Available in 13 mm, 25 mm, and 33 mm diameters with pore sizes of 0.22 and 0.45 micron, the filters support a range of membrane types including Nylon, PES, CA, MCE, PTFE, PVDF, RC, and PP.

Individually packed and gamma sterilized to eliminate microbial contamination in sensitive applications
Available in 13 mm, 25 mm, and 33 mm diameters with 0.22 and 0.45 micron pore sizes for flexible sample handling
Injection-moulded sealing provides a robust seal that withstands pressure without adhesive leaching
Multiple membrane options cover aqueous, organic, and protein-containing samples without changing geometry

Key Benefits

What This Product Gives You

Individually packed and gamma sterilized to eliminate microbial contamination in sensitive applications
Available in 13 mm, 25 mm, and 33 mm diameters with 0.22 and 0.45 micron pore sizes for flexible sample handling
Injection-moulded sealing provides a robust seal that withstands pressure without adhesive leaching
Multiple membrane options cover aqueous, organic, and protein-containing samples without changing geometry
Packing formats include 100 pieces per pack for 13 mm and 50 pieces per pack for 25 mm and 33 mm sizes

Sterilized by gamma radiation for microbial-free use in sensitive applications
Maximum operating temperature of 50°C, suitable for warm solvents and heated samples
Maximum operating pressure greater than 87 psi (approximately 6 bar at 23 C)
Filtration areas of 0.92 cm² (13 mm), 3.9 cm² (25 mm), and 4.9 cm² (33 mm)
Female luer lock inlet and male luer slip outlet for secure connection to standard syringes
Injection-moulded sealing ensures no adhesive in the flow path and high pressure resistance

Where It Is Used

Applications And Buyers

Application Scenarios

Sterile filtration of cell culture media and buffer solutions in biotechnology labs
Preparing samples for HPLC and GC analysis where extractables must be minimized
Filtering protein solutions and biological fluids that require low protein binding
Processing environmental and pharmaceutical samples with high particulate loads
Supporting routine QC testing in regulated laboratories requiring gamma-sterilized consumables

Who It Is For

Biopharmaceutical and life-science laboratories requiring gamma-sterilized filters for cell culture and assay prep
Pharmaceutical QC labs running HPLC methods sensitive to extractables from filter materials
Environmental testing labs handling samples with high microbial or particulate content
Contract research organisations needing consistent, sterile filtration across multiple projects
Lab distributors sourcing gamma-sterilized filters with multiple membrane options in standard formats

Problems It Solves

Microbial contamination in sterile samples due to non-sterile filters or improper handling
Ghost peaks and baseline noise in HPLC caused by extractables from multi-layer or solvent-bonded filters
Filter failure under pressure due to weak seals or adhesive degradation
Inconsistent membrane performance when switching between different filter brands with varying geometries
Lack of gamma sterilization in filters used for sensitive biological or cell-based assays

Data

Specifications

Filter Media	Nylon, PTFE, Hydrophilic PTFE, MCE, RC, CA, PES, PVDF, Hydrophilic PVDF, PP, GF
Diameter	13 mm, 25 mm, 33 mm
Pore Size	0.22, 0.45 micron
Max Operating Temperature	50°C
Max Operating Pressure	>87 psi
Filtration Area	0.92 cm² (13 mm), 3.9 cm² (25 mm), 4.9 cm² (33 mm)
Inlet / Outlet	Female luer lock / male luer slip
Sterilization	Gamma radiation
Packing	100 pcs per pack (13 mm), 50 pcs per pack (25 mm, 33 mm)

Materials

Membrane selected per application: Nylon, PTFE, Hydrophilic PTFE, MCE, RC, CA, PES, PVDF, Hydrophilic PVDF, PP, GF

Customization Options

OEM labeling available for private-label branding
Choice of nine membrane types across 0.22 and 0.45 micron pore sizes
13 mm, 25 mm, and 33 mm diameters with standard packing formats
OEM contract manufacturing and membrane die-cut and packing services available

How It Is Made

Manufacturing And Quality Control

Manufacturing Process

Membrane die cutting to precise dimensions
Injection-moulded sealing of the membrane into the housing
Gamma radiation sterilization of individual filters
Labeling and packing in 100-piece (13 mm) or 50-piece (25 mm, 33 mm) packs

Quality Control

Membrane and housing inspected before assembly
Sealing integrity tested to ensure no leakage at operating pressure
Sterilization validation confirmed via gamma radiation dose monitoring
Pore size and membrane type verified against the part number printed on the housing

Comparison

Compared With The Alternatives

Versus Non-sterilized syringe filters

Gamma sterilization eliminates microbial load, which is critical for cell culture and sterile assay workflows where contamination risks are unacceptable.

Versus Solvent-bonded filters

Injection-moulded sealing avoids adhesive in the flow path, reducing extractables and improving compatibility with sensitive analytical methods.

Versus Multi-layer filters

Single-layer membrane construction minimizes material contact and extractables, which is essential for gradient HPLC and low-level detection methods.

Versus Reusable filter holders

Single-use gamma-sterilized filters eliminate carry-over risk and cleaning validation burden, especially in regulated environments.

Use Guide

How To Use It

Select membrane type based on sample chemistry: PTFE and PP for aggressive solvents, PES and MCE for aqueous samples, Nylon and RC for mixed phases
Use 0.22 micron for sterile filtration and 0.45 micron for routine particulate removal
Choose 13 mm for small volumes (up to a few mL), 25 mm for moderate volumes, and 33 mm for high-volume or high-particulate samples
Attach syringe to female luer lock inlet, expel air, and filter at a steady rate to avoid pressure spikes
Discard the first few drops if the method is sensitive to wetting solvent or extractables
Do not exceed 87 psi or 50°C; if pressure rises rapidly, switch to a larger diameter or coarser pore size

Photos

Product Gallery

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FAQ

Questions Buyers Ask

Are these filters gamma sterilized?

Yes, each Sterifil™ syringe filter is individually sterilized by gamma radiation to ensure microbial-free use in sensitive applications.

What is the maximum operating pressure?

The maximum operating pressure is greater than 87 psi, which is approximately 6 bar at 23 C.

What pore sizes are available?

Available pore sizes are 0.22 micron and 0.45 micron for all membrane types.

What are the packing quantities?

13 mm filters are packed 100 per pack; 25 mm and 33 mm filters are packed 50 per pack.

Can I use these for sterile filtration of cell culture media?

Yes, the gamma sterilization and low extractables make these suitable for sterile filtration of cell culture media and biological samples.

Do you offer OEM labeling?

Yes, OEM labeling and private-label packing are available through the Microlab OEM division.