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Syringe Filter

Chromfil Syringe Filter

Chromfil™ Syringe Filters are designed for routine and demanding sample clarification in analytical laboratories. The filters are available in 13 mm and 25 mm diameters with a range of membrane types including Nylon, PTFE, PVDF, CA, PES, MCE, RC, PP, and GF. The multi-layer membrane structure with a PP or GF prefilter enhances durability and extends filter life when processing dirty or high-particulate samples. Injection-moulded sealing ensures a robust seal under pressure, and the housing is made from virgin medical polypropylene. These filters are intended as a direct replacement for Whatman's Puradisc syringe filters, maintaining compatibility with standard syringe fittings and laboratory workflows.

  • Multi-layer membrane structure with PP or GF prefilter extends filter life in high-particulate or dirty sample matrices
  • Injection-moulded sealing withstands 6 bar at 23 C, reducing the risk of housing failure during high-pressure filtration
  • Available in 13 mm and 25 mm diameters to suit small to larger sample volumes and higher particle loads
  • Multiple membrane options cover aqueous, organic, and mixed-phase samples, supporting diverse analytical applications
Key Benefits

What This Product Gives You

  • Multi-layer membrane structure with PP or GF prefilter extends filter life in high-particulate or dirty sample matrices
  • Injection-moulded sealing withstands 6 bar at 23 C, reducing the risk of housing failure during high-pressure filtration
  • Available in 13 mm and 25 mm diameters to suit small to larger sample volumes and higher particle loads
  • Multiple membrane options cover aqueous, organic, and mixed-phase samples, supporting diverse analytical applications
  • Direct replacement for Whatman's Puradisc syringe filters, enabling method continuity without revalidation
  • Multi-layer membrane structure with PP or GF prefilter for extended life in dirty samples
  • Injection-moulded sealing technology for robust seal integrity at 6 bar at 23 C
  • Housing made from virgin medical polypropylene, non-recycled
  • Available in 13 mm and 25 mm diameters with filtration areas of 1.09 cm² and 4.08 cm² respectively
  • Female luer lock inlet and male luer slip outlet for compatibility with standard laboratory syringes
  • Pore sizes from 0.1 to 5.0 micron across all membrane types
  • Part numbers clearly indicate membrane type, diameter, pore size, and packing
Where It Is Used

Applications And Buyers

Application Scenarios

  • Clarifying HPLC and GC sample extracts before injection to prevent column fouling
  • Filtering tissue culture media and biological buffers containing particulates or protein aggregates
  • Processing environmental water samples with high organic or particulate content
  • Handling pharmaceutical eluates and dissolution samples with variable viscosity and particulate load
  • Supporting high-throughput workflows in QC labs where filter longevity reduces consumable change frequency

Who It Is For

  • Pharmaceutical QC laboratories processing high volumes of complex biological and organic samples
  • Environmental and food testing labs handling dirty matrices like soil leachates, beverage extracts, and edible oils
  • Life-science labs requiring durable filters for cell culture supernatants and protein solutions
  • Laboratory distributors seeking a full membrane range from one supplier with consistent geometry
  • OEM partners needing a reliable filter platform for private-label or contract manufacturing

Problems It Solves

  • Column frits clogging prematurely due to unfiltered particulates in sample matrices
  • Filter failure under pressure when processing viscous or particle-laden samples
  • Short filter life in dirty samples due to single-layer membrane limitations
  • Inconsistent performance across multiple membrane types from different suppliers with varying geometries
  • Need to revalidate methods when switching between filter brands due to differences in housing or sealing
Data

Specifications

Filter MediaNylon, PTFE, Hydrophilic PTFE, MCE, RC, CA, PES, PVDF, Hydrophilic PVDF, GF, PP
HousingPP
Diameter13 mm, 25 mm
Filtration Area1.09 cm² (13 mm), 4.08 cm² (25 mm)
Pore Size0.1, 0.22, 0.45, 1.0, 3.0, 5.0 micron
Sealing TechnologyInjection molding
Max Operating Pressure6 bar at 23 C
Inlet / OutletFemale inlet lock / male outlet slip
Packing100 pcs per pack

Materials

  • Membrane selected per application: Nylon, PTFE, Hydrophilic PTFE, MCE, RC, CA, PES, PVDF, Hydrophilic PVDF, GF, or PP

Customization Options

  • Choice of nine membrane types across 0.1 to 5.0 micron pore sizes
  • 13 mm and 25 mm housing diameters
  • OEM printing and private-label packing available through the Microlab OEM division
  • OEM contract manufacturing and membrane die-cut and packing services for filter brands
How It Is Made

Manufacturing And Quality Control

Manufacturing Process

  • Membrane die cutting for precise sizing and alignment
  • Injection-moulded sealing of the multi-layer membrane into the housing
  • Ultrasonic melting for enhanced seal integrity and structural stability
  • Part number and membrane type printed on the housing
  • Packing at 100 pieces per pack

Quality Control

  • Membrane and housing inspected before assembly
  • Sealing integrity tested to 6 bar at 23 C to ensure no leakage
  • Pore size and membrane type verified against the printed part number
  • Filtration area measured to match specified values for 13 mm and 25 mm formats
Comparison

Compared With The Alternatives

Versus Single-layer syringe filters

The multi-layer structure with PP or GF prefilter improves durability and extends life when filtering dirty or high-particulate samples, though it adds more material to the flow path.

Versus Solvent-bonded housings

Injection-moulded sealing avoids adhesive residues in the flow path and provides a higher pressure rating of 6 bar at 23 C.

Versus Whatman's Puradisc syringe filters

Chromfil™ is specified as a direct replacement, so the same geometry, membrane options, and performance are maintained without method revalidation.

Versus Reusable filter holders

A reusable holder reduces consumable cost but requires cleaning and carries carry-over risk; a single-use filter eliminates both issues.

Use Guide

How To Use It

  • Select the membrane based on sample chemistry: PTFE and PP for aggressive solvents, PES and MCE for aqueous samples, Nylon and RC for mixed phases
  • Use 13 mm for sample volumes up to a few millilitres; 25 mm for larger volumes or higher particle loads
  • Choose 0.45 micron for routine HPLC clean-up; 0.22 micron for sterile-grade or fine particulate removal
  • Attach the syringe to the female luer lock inlet, expel air, and filter at a steady rate
  • Discard the first few drops if the method is sensitive to the membrane wetting solvent
  • Do not exceed 6 bar at 23 C; if pressure rises sharply, switch to a larger diameter or coarser pore size
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FAQ

Questions Buyers Ask

Which membrane should I use for organic solvent samples?

For organic solvents, use hydrophobic PTFE or PP membranes. They are chemically resistant and maintain integrity in aggressive solvents.

What is the difference between the 13 mm and 25 mm sizes?

The 13 mm filter has a 1.09 cm² filtration area and is suitable for small volumes. The 25 mm filter has 4.08 cm² and handles larger volumes or higher particle loads before blocking.

Can Chromfil™ replace Whatman's Puradisc filters?

Yes. Chromfil™ is specified as a direct replacement for Whatman's Puradisc syringe filters in the same 13 mm and 25 mm diameters.

What is the maximum pressure the filter can handle?

The filter is rated for 6 bar at 23 C. The injection-moulded sealing technology ensures the housing does not fail under this pressure.

How are the filters packed?

Standard packing is 100 pieces per pack. Each housing is printed with the membrane type, pore size, and part number for easy identification.

Do you offer private-label options?

Yes. The Microlab OEM division provides OEM printing, private-label packing, and contract manufacturing services for filter brands.

Get A Quote For Chromfil Syringe Filter

Tell us the membrane, pore size, diameter and quantity you need, or describe the sample and we will specify it.