Humectant mild preservative and solvent for preservative-free claims
1,2-Hexanediol is the ingredient formulators use when the brief says hydration, shelf life and a lighter skin feel at the same time. It hydrates by attracting and retaining moisture without tackiness, acts as a mild preservative or preservative booster that extends shelf life, and works as a solvent that improves texture and emulsion stability. Paired with p-hydroxyacetophenone it is the backbone of many preservative-free claims.
CAS 6920-22-5 Preservatives With Humectant Properties
Humectant, mild preservative and solvent in a single ingredient, which shortens the raw material list and the number of incoming inspections.
It holds moisture in the skin without the tackiness that higher glycerin loads introduce, so serums and lotions stay light.
At around 5 percent it functions as a mild preservative, often paired with p-hydroxyacetophenone for formulations marketed without conventional preservatives.
As a solvent it helps disperse pigment and holds emulsions together in foundations, lipsticks and eyeliners.
| Purity grades | Available in high purity grades of 99.5 percent and above |
|---|---|
| Regulatory status | Complies with major international cosmetic regulations |
| Skincare dosage | 0.5 to 5 percent for hydration and preservation |
| Haircare dosage | 1.5 to 2 percent for moisture and antimicrobial protection |
| CAS No. | 6920-22-5 |
|---|---|
| Purity | High purity grades, 99.5 percent and above |
| Skincare use level | 0.5 to 5 percent in creams, lotions, serums and masks |
| Haircare use level | 1.5 to 2 percent in conditioners and shampoos |
| Preservative function | Effective as a mild preservative or booster at around 5 percent |
| Packaging | 25 kg drum, 50 kg drum |
| Hazard classification | Causes serious eye irritation, GHS H319 |
| Appearance | TBC on request |
We partner only with manufacturers that have proven track records and modern facilities. Certificates of Analysis are provided for every shipment, and products are produced to meet relevant standards such as ISO, USP and EP where applicable.
The manufacturer is audited before the first order, not after a complaint.
Every shipment carries a Certificate of Analysis tied to the lot you receive.
MSDS/SDS, Certificate of Origin and the commercial and transport documents travel with the goods.
Safety information above comes from the product documentation for 1,2-Hexanediol. Confirm every limit against the regulation in force in your destination market before you commit a formulation to production.
| Option | Behaviour | Best suited to |
|---|---|---|
| 1,2-Hexanediol | Humectant, mild preservative and solvent, effective around 5 percent | Preservative-free positioning and light textures |
| Glycerin | Pure humectant at 5 to 15 percent, no preservation | Cost-effective hydration and barrier support |
| Phenoxyethanol | Broad-spectrum preservative capped at 1.0 percent | Primary preservation of aqueous products |
| Ethylhexylglycerin | Booster and conditioner at 0.3 to 1.0 percent | Lifting the performance of a preservative |
Drum sizes listed in the specification table, or packaging as per customer request.
Document pack prepared for your destination market, whether EU, United States or China NMPA.
For blended systems, the ratio can be discussed against the formulation you are preserving.

Broad-spectrum cosmetic preservative effective against bacteria yeast and mould
CAS 122-99-6 →
USP grade humectant for hydration barrier support and texture control
CAS 56-81-5 →Synergistic preservative system dosed as a single raw material
CAS 122-99-6 and 70445-33-9 →Preservation and hydration for creams lotions serums and masks
Pigment dispersion and emulsion stability for foundations lipsticks and eyeliners
Preservation for facial washes shower gels and wet wipes
Preservation for surfactant systems and moisture for conditioners
From preservative selection to challenge test results
Moisture claims that survive substantiation and sensory panels
One is a capped broad-spectrum preservative, the other a multifunctional humectant with mild preservation. The difference decides your label claim as much as your shelf life.
Buying GuideA four-question method for picking between phenoxyethanol, 1,2-hexanediol, a booster and a ready-made blend, with the dosage limits that apply to each.
It is effective as a mild preservative or booster at around 5 percent and is often paired with p-hydroxyacetophenone for formulations marketed as preservative-free. Validate the result with challenge testing before you rely on it alone.
0.5 to 5 percent in creams, serums and shampoos. Exceeding 5 percent may cause skin dryness or irritation without improving efficacy.
No. It hydrates by attracting and retaining moisture with a non-sticky feel, which is the main reason formulators choose it over higher glycerin levels in serums.
It causes serious eye irritation, GHS H319. Eye protection is required and any exposure must be rinsed immediately.
High purity grades of 99.5 percent and above, compliant with major international cosmetic regulations.
25 kg drums and 50 kg drums.
Send the grade, the annual volume, the packaging you prefer and the destination market. Pricing and the document pack come back within 24 hours.