What This Grade Is For
Hydroxypropyl Methylcellulose (HPMC) for Pharmaceuticals is supplied by Yiyuantong Chemical as a binder, film former and controlled-release matrix polymer. Coating: The coating agent is made into a solution of organic solvent or aqueous solution for tablets, especially for spray coating of the prepared granules. Suspension agent: The effect is shown in 4-5 days with a dosage of 2-3 grams per day and 1-2 grams each time.
Key Benefits
- Acts as a binder and film former for tablets and coatings
- Builds a hydrophilic matrix used for sustained release formats
- Used as a lubricant in ophthalmic products and as an excipient in oral dosage forms
- Export packed and documented for container shipment, with lot analysis issued before departure
Problems It Solves
- Tablets that cap or laminate because the binder gives too little plastic bonding
- Release profiles that vary between batches of excipient
- Film coats that crack or peel on curved tablet faces
Application Scenarios
- Tablet binding and film coating
- Sustained release matrix tablets
- Ophthalmic solutions
- Ointments, emulsions, jellies and suppositories
Who It Is For
- Pharmaceutical manufacturers
- Excipient distributors
- Contract dosage form developers
Technical Features
- High water retention lets cement hydrate fully and raises bonding strength
- Improves tensile and shear strength in plastering mortar
- Reduces sagging and cracking in putty and skim coat work
- Acts as a retarder in gypsum, solving drumming and early strength problems
- Used as an excipient and as a lubricant in ophthalmic formulations
Technical Data And Packing
| Appearance | powder |
|---|---|
| Viscosity | 100-70000 mPa.s |
| Moisture | content 5≤% Hydroxypropyl content 15-30% |
| Package | 25kg/bag Storage six months |
Packing is 25 kg per bag as standard: an inner polyethylene plastic film bag inside an outer composite plastic woven bag. Other pack sizes are arranged on request.
Raw Materials
- Refined cellulose
- Methyl chloride
- Propylene oxide
Manufacturing Process
- Alkalisation of refined cellulose
- Mixed etherification
- Washing and purification
- Drying and milling
- Lot testing and packing
Quality Control
- Every lot is tested in our own laboratory against the customer specification before release
- Third-party verification is available through SGS, which we have worked with on export lots
- Certificate of analysis issued with each shipment; HPLC or NMR data supplied on request
- Acetone countercurrent washing removes process residues before drying and milling
How It Compares
| Povidone | Cellulose ether gives a hydrophilic matrix useful where sustained release is the target |
|---|---|
| Hydroxyethyl cellulose | HPMC is the more usual choice for oral solid dosage forms; HEC is common in ophthalmic and topical systems |
Use Guide
- Qualify the grade against your own dissolution method before a production batch
- Request the certificate of analysis and, where needed, HPLC or NMR data for incoming inspection
Customisation Options
- Viscosity grade selected against your process, from 300 to 200000 mPa.s
- Private label bags printed with your own label content
- Packing sizes arranged to suit your blending line
- Sample shipment by FEDEX, DHL or EMS before a production order
Certification And Inspection
- SGS third-party inspection available on export lots
- Certificate of analysis issued with every shipment
- HPLC or NMR data supplied on request
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View SpecificationHydroxypropyl Methylcellulose (HPMC) for Pharmaceuticals FAQ
Can you supply pharmaceutical grade material?
Grade availability and the supporting documentation should be confirmed for your market before ordering. We will send the certificate of analysis, and HPLC or NMR results on request.
Do you provide samples for qualification?
Yes. Samples go out by FEDEX, DHL or EMS. Some are free of charge and you cover the freight.
Are you a manufacturer or a trading company?
We are a manufacturer and you are welcome to visit the plant. Our hydroxyethyl cellulose project runs at 5000 tonnes a year on an acetone countercurrent washing process.
What payment terms do you accept?
L/C, T/T, D/A, D/P, PayPal and Western Union. We have worked with China Export and Credit Insurance Corporation for many years.
How fast can you ship?
Stock items are despatched within 5 days of payment. If the grade is not in stock, production and despatch take 7 to 10 days from payment.
Get A Price For Hydroxypropyl Methylcellulose (HPMC) for Pharmaceuticals
Send the quantity, the viscosity grade and the destination port. We reply with price, lead time and the lot analysis.